Transporters and diabetes-related retinal damageTwo transporters that deliver alternative energy sources to the eye may help delay retinal damage that can occur in diabetes, scientists say.
The transporters, SMCT1 and SMCT2, can circumvent the eye's protective blood-retinal barrier, delivering energy sources lactate and ketone bodies to a healthy eye, says Dr. Pamela Martin, biochemist at the Medical College of Georgia.
In diabetes, characterized by plenty of glucose but the inability........Go to the Diabetes-news-blog (Added on 11/28/2007 9:56:44 PM)
Pedometers motivate people with diabetes to walk moreThe use of a pedometer and a Web site that tracked physical activity levels proved to be powerful motivators for people with diabetes who participated in a recent walking study conducted by scientists from the University of Michigan Health System and VA Ann Arbor Healthcare System. The study also suggests that certain types of goal-setting may be more effective than others.
All participants in the study wore pedometers and received automated........Go to the Diabetes-watch-blog (Added on 11/19/2007 8:22:46 PM)
Gene's Role in Type 1 DiabetesScientists at the University of Virginia Health System have identified an enzyme believed to be an important instigator of the inner-body conflict that causes Type 1 diabetes. A chronic condition that affects nearly three million American children and adults, Type 1 diabetes is more severe than Type 2. Type 1 diabetes, also called autoimmune diabetes, arises when the body's infection-fighting white blood cells start destroying the beta-cells........Go to the Diabetes-watch-blog (Added on 11/7/2007 7:49:34 PM)
High Blood Pressure Heart Disease And DiabetesHigh-blood-pressure patients treated for enlarged heart (left ventricular hypertrophy, LVH) who have regression or prevention of LVH may also have a better chance of preventing diabetes. Led by physician-researchers at NewYork-Presbyterian Hospital/Weill Cornell Medical Center, the research is reported in the November Hypertension, a journal of the American Heart Association (AHA).
An estimated 20 percent of all high-blood-pressure patients,........Go to the Diabetes-watch-blog (Added on 10/31/2007 7:19:21 PM)
The new source of islet cellsThe shortage of islet cells limits the development of islet transplantation. One new approach was published in the October 21 issue of the World Journal of Gastroenterology because of its great significance in enhancing the output of islet cells. This article will undoubtedly bring benefit to diabetic patients.
The article describes the differentiation of rat pancreatic ductal epithelial cells into insulin-producing cells by the transfection........Go to the Diabetes-watch-blog (Added on 10/26/2007 5:11:41 AM)
Potential role of leptin in diabetesA new Joslin-led study has shown that leptin, a hormone known mainly for regulating appetite control and energy metabolism, plays a major role in islet cell growth and insulin secretion. This finding opens up new avenues for studying leptin and its role in islet cell biology, which may lead to new therapys for diabetes. This study appears in the October 2007 issue of The Journal of Clinical Investigation.
Prior in vitro studies suggested........Go to the Diabetes-watch-blog (Added on 10/1/2007 9:09:52 PM)
Smart Insulin Nanostructures Pass Feasibility TestBiomedical engineers at The University of Texas School of Health Information Sciences at Houston have announced pre-clinical test results in the recent issue of the International Journal of Nanomedicine demonstrating the feasibility of a smart particle insulin release system that detects spikes in glucose or blood sugar levels and releases insulin to counteract them.
Designed to mimic functions of the pancreas which produces the blood-sugar........Go to the Diabetes-watch-blog (Added on 9/21/2007 5:34:04 AM)
How Cells From Pigs May Cure DiabetesWithin three years, insulin-producing islet cells from pigs may be used in clinical trials on a path to finally cure insulin dependant diabetes.
This key finding was the discovery of Dr. Bernhard Hering, Scientific Director of the Diabetes Institute for Immunology & Transplantation at the University of Minnesota and his team, who documented their medical breakthrough in the prestigious scientific journal Nature Medicine in March of 2006.
........Go to the Diabetes-watch-blog (Added on 9/12/2007 7:58:24 PM)
How insulin secreting cells maintain their glucose sensitivityResearchers at the leading Swedish medical university Karolinska Institutet have now disclosed the mystery how the insulin-secreting cells maintain an appropriate number of ATP sensing ion channel proteins on their surface. This mechanism, which is described in the latest number of Cell Metabolism, explains how the human body can keep the blood glucose concentration within the normal range and thereby avoid the development of diabetes.
Blood........Go to the Diabetes-news-blog (Added on 9/6/2007 5:08:13 AM)
Treating diabetes during pregnancyTreating diabetes during pregnancy can break the link between gestational diabetes and childhood obesity, as per a Kaiser Permanente study featured in the recent issue of Diabetes Care.
The largest study of its kind, this research shows that the risk of childhood obesity rises in tandem with a pregnant womans blood sugar level and that untreated gestational diabetes nearly doubles a child's risk of becoming obese by age 5 to 7. The study........Go to the Diabetes-watch-blog (Added on 8/28/2007 9:22:37 PM)
Reducing inflammation plays as type 1 diabetes therapyBOSTON -- Scientists at Beth Israel Deaconess Medical Center (BIDMC) have observed that a triple combination treatment consisting of both tolerance-inducing and anti-inflammatory properties is successful in abolishing adverse autoimmunity against insulin-producing cells in a mouse model of Type 1 diabetes.
The findings, which appear in the Online Early Edition of the Proceedings of the National Academy of Sciences (PNAS) this week, offer a........Go to the Diabetes-watch-blog (Added on 7/31/2007 9:48:37 PM)
Insulin grown in plants relieves diabetes in miceCapsules of insulin produced in genetically modified lettuce could hold the key to restoring the bodys ability to produce insulin and help millions of Americans who suffer from insulin-dependent diabetes, as per University of Central Florida biomedical researchers.
Professor Henry Daniells research team genetically engineered tobacco plants with the insulin gene and then administered freeze-dried plant cells to five-week-old diabetic mice as........Go to the Diabetes-watch-blog (Added on 7/30/2007 8:18:14 PM)
Shielding the brain from too much insulin can prolong lifeOne route to a long and healthy life may be establishing the right balance in insulin signaling in the body and brain, as per new research from Children's Hospital Boston. The study, reported in the July 20 issue of Science, not only reinforces the value of exercising and eating in moderation, but also helps explain a paradox in longevity research.
Insulin sends a vital signal in the body, telling cells to use sugar from the blood. When........Go to the Diabetes-news-blog (Added on 7/19/2007 10:40:48 PM)
Rapid-acting insulin: superiority not provenThere is currently no evidence available of a superiority of rapid-acting insulin analogues over human insulin in the therapy of adult patients with diabetes mellitus type 1. The evidential value and design of studies available so far are inadequate and do not allow conclusions regarding most patient-relevant treatment goals, such as the reduction in long-term complications or overall mortality. Due to the lack of data, the benefit of........Go to the Diabetes-watch-blog (Added on 7/17/2007 10:23:14 PM)
Gene discovered for type 1 diabetes in childrenPediatrics scientists at The Childrens Hospital of Philadelphia and McGill University in Montreal have identified a gene variant that raises a childs risk for type 1 diabetes, formerly called juvenile diabetes. As researchers continue to pinpoint genes contributing to diabetes, they have their eyes on providing a scientific basis for designing better therapys and preventive measures for the disease.
The research adds a new gene and new........Go to the Diabetes-watch-blog (Added on 7/15/2007 9:11:01 PM)
Pumpkin: A fairytale end to insulin injections?Compounds found in pumpkin could potentially replace or at least drastically reduce the daily insulin injections that so a number of diabetics currently have to endure. Recent research reveals that pumpkin extract promotes regeneration of damaged pancreatic cells in diabetic rats, boosting levels of insulin-producing beta cells and insulin in the blood, reports Lisa Richards in Chemistry & Industry, the magazine of the SCI.
A group, led by........Go to the Diabetes-watch-blog (Added on 7/8/2007 10:12:59 PM)
Pharmacists To Help Diabetes SufferersA new Wesley Research Institute project aims to make it much easier for people to manager their Type 2 Diabetes by using community pharmacists.
There are more than one million Australians with Type 2 Diabetes who are at an increased risk of developing serious health problems including heart disease, stroke, kidney disease and blindness.
Chief investigator of the project, Mr David Brand of The Wesley Pharmacy, said this study had the........Go to the Diabetes-news-blog (Added on 7/5/2007 9:44:04 PM)
helping obese diabetics lose weightA plate and cereal bowl with markers for proper portion sizes appear to help obese patients with diabetes lose weight and decrease their use of glucose-controlling medications, according to a report in the June 25 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.
Between 1960 and 2000, the proportion of U.S. adults who were obese increased from 13.4 percent to 30.9 percent, according to background information in the........Go to the Diabetes-news-blog (Added on 6/25/2007 9:20:14 PM)
Potential New Target For Type 2 DiabetesResearchers at the University of Pennsylvania School of Medicine have discovered a potential new target for treating type 2 diabetes, according to a new study that appeared online this week in Nature. The target is a protein, along with its molecular partner, that regulates fat metabolism.
“Over the last 10 years, we have begun to understand the importance of fat metabolism in diabetes,” notes lead author Morris J. Birnbaum, MD, PhD, the........Go to the Diabetes-news-blog (Added on 6/10/2007 8:54:52 PM)
Sleep apnea may increase risk of diabetesScientists at the Yale University School of Medicine have observed that patients with obstructive sleep apnea are at increased risk for developing of type II diabetes, independent of other risk factors. The findings are being presented at the American Thoracic Society 2007 International Conference, on Monday, May 21.
The study looked at 593 patients at the VA Connecticut Health Care System referred for evaluation of sleep-disordered........Go to the Diabetes-news-blog (Added on 5/21/2007 11:43:08 AM)
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Fall 2006 FashionFashion week is over in New York City and fall styles have been released. It always amazes me to be talking about fall styles when spring has not even sprung yet. Here it is! Colors are dark and neutral but accessories are sizzling and spruce up those colors of the evening. There is plenty to keep from this winter season and plenty to get rid of.
Let us start with colors. Think of nightfall when it comes to fall color as per Pantone. The........Go to the Fashion-blog (Added on 2/26/2006 4:47:03 PM)
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